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About Free Radicals and Antioxidants

Free Radicals and Antioxidants [ISSN: 2231-2536] is an online peer reviewed publication dedicated to publishing novel, original findings in the field of free radical biology and both natural and synthetic antioxidants. Free radicals, which are defined as molecules containing one or more unpaired electrons in their outmost atomic or molecular orbital have emerged as double edged swords. Recent research has revealed that they can be both beneficial (e.g. in microbicidal activity inside neutrophils) or deleterious (e.g. lipid peroxidation and membrane damage). Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are the two major classes of free radicals. The generation of these reactive species is tightly controlled by enzymes like nitric oxide synthase (NOS) and NAD (P)H oxidase. Mechanisms exist inside cells that both generate and protect against ROS-induced oxidative damage. This equilibrium termed as “redox homeostasis” is vital for the health and continued survival of the cell. The Free Radicals and Antioxidants Journal aims to foster the dissemination of scientific information by publishing manuscripts that provide new insights into the biology of free radicals, including their generation, degradation, modulation, role in cellular function and cell signaling. The submission of uninvited expert reviews and research articles in all areas of Free Radical Biology and Antioxidants are also welcomed. Free Radicals and Antioxidants publishes full research papers presenting original, high quality research, critical review articles providing comprehensive analysis of research development within a defined area and editorial commentaries on key topical issues in Free Radical and Antioxidant Biology.