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Published on:17th May 2010
Pharmacognosy Journal, 2010; 2(9):248–253
original Article | doi:Nill

Pharmacognostical Evaluation of Fruits of Solanum lycocarpum A. St.-Hill. (Solanaceae)


Authors and affiliation (s):

Araújo M. G. F.1*, Galeane M. C.2, Castro A. D.3, Salgado H. R. N.3, Almeida A. E.3, Cunha W. R.4, Veneziani R. C. S.4, Moreira R. R. D.2

1Departamento de Ciências Biológicas, Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, Rodovia Araraquara-Jaú km 1, 14801-902, Araraquara, SP, Brasil.

2Departamento de Princípios Ativos Naturais e Toxicologia, Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, Rodovia Araraquara-Jaú km 1, 14801-902, Araraquara, SP, Brasil.

3Departamento de Fármacos e Medicamentos, Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, Rodovia Araraquara-Jaú km 1, 14801-902, Araraquara, SP, Brasil.

4Núcleo de Pesquisas em Ciências Exatas e Tecnológicas, Universidade de Franca. Av. Dr. Armando Salles de Oliveira, 201, Parque Universitário, 1440-600, Franca, SP, Brasil

Abstract:

This study describes the chemical and physical-chemical profile of plant drug and ethanolic extract obtained from fruits of Solanum lycocarpum A. St.-Hill. (Solanaceae). The physical and chemical analysis involved the granulometry determination, non-compacted apparent density, loss on drying in oven and in infrared scale, pH, ash values and extractive values. The results determined the physical-chemical characteristics of the drug plant. It was also carried out the microbiological control of the plant drug. The preliminary phytochemical screening featured the presence of tannins, flavonoids and saponins in the plant drug and alkaloids and steroids in the ethanolic exctract. The solamargine and solasonine glycoalkaloids were identified through TLC and GC/MS. The levels of total phenols and tannins were quantified in the extract (8.90% and 6,85% respectively). Such studies contribute to the chemical identification and quality control of S. lycocarpum fruits.

Key words: Solanum lycocarpum, phytochemical screening, pharmacognostical evaluation, total phenolic compounds, solasonine, solamargine.

 

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