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Published on:9, 2011
Pharmacognosy Journal, 2011; 3(25):91-93
Original Article | doi:10.5530/pj.2011.25.16

Diuretic Activity of Alcoholic Extract of Musa sapientum L. Flower


Authors and affiliation (s):

Ashutosh Mishra1, Manas Ranjan Mishra1, Dusmanta Kumar Pradhan1*, Sunil Kumar Vaishnav2

1Gayatri College of Pharmacy, Jamadarpali, Sambalpur, Odisha-768200.

2JK College of Pharmacy, Bilaspur, CG.

Abstract:

The present study was designed to investigate the diuretic activity of Musa sapientum L. (family- Musaceae) flowers. The dried powder of the flower was subjected to Soxhlet extraction with alcohol and this extract was used for diuretic activity in Wistar albino rats using Lipschitz method. The diuretic activity was assessed in terms of urine output and, concentration of Sodium, Potassium and Chloride ions in urine. The result obtained revealed that the alcoholic extract showed significant diuretic activity at a dose of 250 and 500 mg/kg body weight by increasing the total volume of urine and, concentration of Sodium, Potassium and Chloride ions with respect to standard drug furosemide.

Key words: Diuretic, Sodium, Potassium, Lipschitz method, Furosemide.

 

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