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Published on:9, 2011
Pharmacognosy Journal, 2011; 3(25):63-66
Original Article | doi:10.5530/pj.2011.25.11

Comparative Molluscicidal Activities of Fruit Pericarp, Leaves, Seed and Stem Bark of Blighia Unijugata Baker

Authors and affiliation (s):

*1Agboola O I, 2Ajayi G O, 2Adesegun S A, and 3Adesanya S A.

1Department of Pharmacognosy and Herbal Medicine, Faculty of Pharmacy, Niger Delta University Wilberforce Island, Bayelsa State.

2Department of Pharmacognosy, Faculty of Pharmacy University of Lagos.

3Department of Pharmacognosy, Faculty of Pharmacy Obafemi Awolowo University Ile-Ife Nigeria.


Introduction: The plant is used in ethno-medicine as a fish poison and belongs to family known to contain saponins which are toxic to cold-blooded animals including snails acting as vectors of organisms responsible for many human diseases including schistosomiasis. Methods: The mollusccidal activities of 50% ethanolic extracts of the seeds, fruit pericarp, leaves and stem bark as well as the fractions of the fruit pericarp of B unijugata Baker were evaluated on Biomphalaria glabrata.snails Results: The crude extract of fruit pericarp was the most active among the morphological parts tested with LC50 of 15 μg/ml while Ethyl- Acetate fractions showed the highest activity of the 3 fractions with a LC50 of 7.6 μg/ml and satisfied the condition set by World Health Organization for a potential plant molluscicides either as a crude extract or as a fractions Conclusions: the results confirmed the ethno-medicinal uses of the plant and can be so regarded as a potential molluscicides in the snail vector of schistsomiasis

Key words: Blighia unijugata, Bak, Fruit pericarp, Biomphalaria glabrata, fruit pericarp, schistosomiasis.


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